2006

See also: 2006 National Lacrosse League season

The Edmonton Rush played their inaugural game and home opener in front of 11,385 fans at Rexall Place in Edmonton, Alberta. The Rush lost 10–9 in overtime to the San Jose Stealth. The game was only the second time in league history that an expansion team forced overtime in their inaugural game.
The 2006 National Lacrosse League All-Star Game was held at the Air Canada Centre in Toronto, Ontario, home of the Toronto Rock. The West Division (Arizona Sting, Calgary Roughnecks, Colorado Mammoth, Edmonton Rush, Portland LumberJax, and San Jose Stealth) defeated the East Division (Buffalo Bandits, Minnesota Swarm, Philadelphia Wings, Rochester Knighthawks, and Toronto Rock) by a score of 14–13 in front of 15,924 fans. Calgary Roughnecks forward Lewis Ratcliff scored the game-winning goal with 4.4 seconds remaining. Ratcliff was named the Game MVP.
The National Lacrosse League finished its 20th season by setting an all-time single season attendance mark, reaching a total of 1,037,147 fans for the 2006 season, including 88 regular-season games, 6 playoff games, the 2006 All-Star Game in Toronto, and the 2006 RBK NLL Championship Game presented by Edge Active Care. The league season average attendance was 10,804.
The Colorado Mammoth defeated the Buffalo Bandits 16–9 in front of 16,104 fans at HSBC Arena in Buffalo to secure the first championship in Colorado Mammoth history. Mammoth forward Gavin Prout was named game MVP, scoring 4 goals and adding 3 assists for 7 points in the win.
The National Lacrosse League announced the awarding of a franchise to New York City for the 2007 season. The official announcement was made during a press conference at East River Park in Manhattan by New York City Mayor Michael Bloomberg and National Lacrosse League Commissioner Jim Jennings. The New York team became the league's 13th franchise and would play its games at Madison Square Garden.

2007

See also: 2007 National Lacrosse League season

The expansion New York Titans played their home opener at Madison Square Garden in the first ever professional lacrosse game at the "World's Most Famous Arena". The Titans defeated the expansion Chicago Shamrox 11–9 in front of 13,127 fans.
The Eastern Division defeated the Western Division 20–16 in front of 12,856 fans at Rose Garden in Portland, Oregon, home of the Portland LumberJax, in the 2007 National Lacrosse League All-Star Game. Buffalo Bandits forward Mark Steenhuis was named the game's Most Valuable Player becoming the first player in NLL history to win 2 All-Star Game MVP honors. Steenhuis had previously won the award in 2004.
The NLL reached a milestone as the league plays its 1,000th regular season game. The Minnesota Swarm hosted the Colorado Mammoth at Xcel Energy Center in Minneapolis/St Paul in the historic game. The Mammoth beat the Swarm 11–9.
The Rochester Knighthawks defeated the Arizona Sting, 13–11, in the 2007 NLL Championship presented by Edge Active Care at Jobing.com Arena. John Grant was named Championship Game MVP with a 3-goal/5-assist performance. The victory marked the first time that Rochester had won the title since 1997.
The NLL reached a new 7-year agreement with the players' union.

2008

See also: 2008 National Lacrosse League season

The league announced the divisional alignments for the 2008 regular season. The expansion Boston franchise would join the Eastern Division, expanding to 8 teams: Boston, Buffalo, Chicago, Minnesota, New York, Philadelphia, Rochester, and Toronto. The Western Division composed of 6 teams remained unchanged: Arizona, Calgary, Colorado, Edmonton, Portland, and San Jose.
John Tavares broke Gary Gait's all-time goal scoring record. Tavares, who had already captured the all-time points and assists records, notched his record-breaking 597th career goal in the third quarter of Buffalo's 17–13 victory over New York.
Philadelphia Forward Athan Iannucci broke Gary Gait's single season scoring record of 61 goals. He went on to finish the season with 71 goals.
The Buffalo Bandits defeated the Portland LumberJax by the score of 14–13 in the 2008 Edge NLL Championship game at HSBC Arena. The event, which aired nationally on ESPN2, drew a sellout crowd of 18,690 fans. Mark Steenhuis captured the game's MVP honors with 5 goals and one assist.

2009

See also: 2009 NLL season

The league announced the addition of i